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It was further proved that the neuroprotective effect of nipradilol against oxidative stress-induced RGCs death was through a HO-1 activity-dependent mechanism by inducing Keap1 S-nitrosylation, Nrf2 nucleus translocation and transcription of HO-1 (a NO-dependent antioxidant enzyme)

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[DOI] [PubMed] [Google Scholar] 48.Martins J., Mendes L., Durães S