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[DOI] [PubMed] [Google Scholar] Krystal JH, Karper LP, Seibyl JP, Freeman GK, Delaney R, Bremner JD, Heninger GR, Bowers MB, Jr., Charney DS

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26 , 27 Thereby, this proof has to be a pleiotropic beneficial effect as the end result of the application of agents that were supposed to have the essential integrative role of the Selye’s (still putative) mediator that integrates the adaptive bodily response to stress 22 , 25 whatever particular mechanism lies behind it