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This shows that the use of unnatural stereochemistry in GSH is unlikely to prevent the substantial first-pass metabolism by GGT in the liver for orally administered GSH, and it is also unlikely to aid in improving its oral bioavailability [31]

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In this same study, the candidate genes BvHMA3 and BvNRAMP3 showed upregulation patterns in response to Cd-toxicity, suggesting that these candidate genes are involved in Cd uptake processes