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Compared with the women who were administered placebo, vitamin B-12–supplemented women had significantly higher plasma vitamin B-12 concentrations in both the second [median vitamin B-12 concentration: 216 pmol/L ( n = 119) vs

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In the SURMOUNT-1 trial, adults on the highest dose lost on average around 22.5% of their body weight over 72 weeks, alongside diet and activity