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Together, these findings suggest that molecular signatures of treatment responsiveness exist, although their translation into consistent and clinically applicable predictive frameworks remains limited 41
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A comparative study of senkyunolide A (100 mg/kg) administered via oral and intravenous routes showed that after intravenous injection, its apparent volume of distribution was 6.74 ± 0.73 L/kg, clearance was 7.2 ± 0.48 L/h, and t1/ 2 was 0.65 ± 0.06 h, reflecting rapid and extensive tissue distribution accompanied by fast systemic clearance
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