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Thus, glutaredoxin makes a significant contribution to the antioxidant protection of cells against the destructive effects of oxidative stress (Figure 2), which causes the formation of intra- and intermolecular disulfide bonds in proteins, the oxidation of functional SH-groups with the formation of sulfonic acid and the subsequent proteosomal degradation of the protein (Ren et al., 2017)

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10.1016/S1388-1981(00)00006-8 Biochim