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The agency said the company failed to meet CGMP requirements, including implementing and adhering to its risk-based corrective and preventive action (CAPA) procedures
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Effects on oxidative stress, tissue remodeling, and inflammation were also observed in a more recent study where quercetin was capable of reducing GATA binding protein 3, TNF-α, transforming growth factor (TGF)-b1, IL-1b, and Acta2 gene expression
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