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Both groups demonstrated strong adherence, with 91.4% in the HAD group and 91.9% in the normal diet group completing the study

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Moreover, as lysosomal function is essential for mitophagy, impairment in the fusion of lysosomes with autophagosomes-containing mitochondria may compromise the clearance of dysfunctional mitochondria, resulting in exacerbated APAP hepatotoxicity