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Why Your Pressors May Not Be Working — Part 3: Receptor Downregulation, You’re giving the pressor…, The dose keeps going up…, But the patient’s blood pressure still isn’t responding the way you’d ...

found that emodin inhibited the HTRA1/TGF-β/NF-κB signaling cascade [61]

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Apomorphine, a recently FDA-appro ved, short-acting, dopamine agonist, is delivered by subcutaneous injection as a rescue dose to manage the sudden and refractory motor fluctuations of L-dopa–induced "off" periods in patients with PD